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Eric Clapton	McDonald's
Botox	Election 2000

Eric Clapton

16 Grammy Awards	raised by grandparents	Derek and the Dominoes	"Layla"
expelled from art college	alcoholism	rock	blues
Cream	Rock & Roll Hall of Fame	"Change the World"	Yardbirds
heroin addiction

McDonald's McNotes

30,000 restaurants
in 121 countries "Did somebody say, 'McDonald's?'" 1948 Dick & Mac McDonald,
San Bernardino, CA '01 Non-U.S. =
60% of sales,
50% of profits Egg McMuffin

'01 sales = $14.8 billion Happy Meals "You deserve a break today" Filet-O-Fish "We love to see you smile"

1961 Kroc buys out
McDonald bros. for $2.7M Chipotle Mexican Grill Jose Bove
French fries
cooked in beef fat "global realization"

"Two all-beef patties…" Chicken McNuggets Boston Market
Monopoly scandal
Value Meals

"McWorld"
'00 employees = 364,000 1954 franchise agreement with Ray Kroc, malt machine salesman Chm & CEO
Jim Cantalupo clean bathrooms, queueing in China

Big Mac World's largest owner of
commercial real estate McLibel case '01 net income = $1.6 billion Hamburgers made
from earthworms

Pret a Manger hot coffee lawsuit Fazoli's obesity lawsuit McD no more than
once a week

Botox

Botulinum toxin Most popular cosmetic procedure in the U.S. Allergan to launch $50 M ad campaign aimed at women. $1.6 M cosmetic Botox procedures in US in 2001 Approved since 1989 to treat muscular spasms or twitches.

possible bioterror weapon 1987 - first used by Dr. Alastair Carruthers "Off-label" use to erase wrinkles is legal. $80 dose =
$300 - $1,000 treatment Made by Allergan, Inc., Irvine, CA

FDA 2002 approval "to temporarily improve the appearance of moderate to severe frown lines between the eyebrows." Won't work for wrinkles caused by loss of elasticity
due to aging, smoking, sun. Allergan, a "conservative company", didn't seek FDA approval until management change in 1998. "Static" wrinkles caused by aging, not muscle contraction? treat with collagen injections. Upper 1/3 of face — "dynamic" muscles contract as part of communication in some cultures. Over time, chronic contraction causes wrinkles.

Self-esteem problem "cured" by injecting a neurotoxin. Botox = possible treatment for migraines, lower back pain, excessive sweating. "Off-label" use is legal, so long as the drug has been approved for something. FDA 2002 approval = can market & advertise as a wrinkle cure Market = 29M women, 30-64 years old, household incomes >$50,000/yr.

Botox sales $130M in 2001, est. growth to $1B in next few years. Japanese don't get face wrinkles as part of communication culture/facial expressions. Blocks acetycholine, a chemical that causes muscles to move. Most users are white females 35-50 years. Too much Botox = mask-like expression.

Purified diluted form of Botulism. Botox takes away the ability to frown. Aging Baby Boomers 12% of customers are men. Botox wears off after 3-4 months.

"In the past if someone came in and wanted plastic surgery, they might be seen as vain or depressed or narcissistic. Today it's seen as a normal desire for social or economic advantage."—Nancy Etcoff, Harvard psychologist, author of Survival of the Prettiest: The Science of Beauty.

Election 2000

30,000 restaurants in 121 countries	"Did somebody say, 'McDonald's?'"	1948 Dick & Mac McDonald, San Bernardino, CA	'01 Non-U.S. = 60% of sales, 50% of profits	Egg McMuffin
'01 sales = $14.8 billion	Happy Meals	"You deserve a break today"	Filet-O-Fish	"We love to see you smile"
1961 Kroc buys out McDonald bros. for $2.7M	Chipotle Mexican Grill	Jose Bove	French fries cooked in beef fat	"global realization"
"Two all-beef patties…"	Chicken McNuggets	Boston Market	Monopoly scandal	Value Meals
"McWorld"	'00 employees = 364,000	1954 franchise agreement with Ray Kroc, malt machine salesman	Chm & CEO Jim Cantalupo	clean bathrooms, queueing in China
Big Mac	World's largest owner of commercial real estate	McLibel case	'01 net income = $1.6 billion	Hamburgers made from earthworms
Pret a Manger	hot coffee lawsuit	Fazoli's	obesity lawsuit	McD no more than once a week

Botulinum toxin	Most popular cosmetic procedure in the U.S.	Allergan to launch $50 M ad campaign aimed at women.	$1.6 M cosmetic Botox procedures in US in 2001	Approved since 1989 to treat muscular spasms or twitches.
possible bioterror weapon	1987 - first used by Dr. Alastair Carruthers	"Off-label" use to erase wrinkles is legal.	$80 dose = $300 - $1,000 treatment	Made by Allergan, Inc., Irvine, CA
FDA 2002 approval "to temporarily improve the appearance of moderate to severe frown lines between the eyebrows."	Won't work for wrinkles caused by loss of elasticity due to aging, smoking, sun.	Allergan, a "conservative company", didn't seek FDA approval until management change in 1998.	"Static" wrinkles caused by aging, not muscle contraction? treat with collagen injections.	Upper 1/3 of face — "dynamic" muscles contract as part of communication in some cultures. Over time, chronic contraction causes wrinkles.
Self-esteem problem "cured" by injecting a neurotoxin.	Botox = possible treatment for migraines, lower back pain, excessive sweating.	"Off-label" use is legal, so long as the drug has been approved for something.	FDA 2002 approval = can market & advertise as a wrinkle cure	Market = 29M women, 30-64 years old, household incomes >$50,000/yr.
Botox sales $130M in 2001, est. growth to $1B in next few years.	Japanese don't get face wrinkles as part of communication culture/facial expressions.	Blocks acetycholine, a chemical that causes muscles to move.	Most users are white females 35-50 years.	Too much Botox = mask-like expression.
Purified diluted form of Botulism.	Botox takes away the ability to frown.	Aging Baby Boomers	12% of customers are men.	Botox wears off after 3-4 months.
"In the past if someone came in and wanted plastic surgery, they might be seen as vain or depressed or narcissistic. Today it's seen as a normal desire for social or economic advantage."—Nancy Etcoff, Harvard psychologist, author of Survival of the Prettiest: The Science of Beauty.